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Steven Lam

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Steven Lam joined the biotechnology group at Goudreau Gage Dubuc in July 2008 as a technical adviser, patents. He brings with him broad technical expertise from working eight years as a research scientist in both academia and industry, and his work has been published and cited in numerous peer-reviewed scientific journals. He graduated from McGill University in 2006 after receiving his doctorate in biochemistry where he trained in the laboratory of Dr. Philippe Gros. Steven Lam won a number of scholarships during his academic career including the Canadian Institutes of Health Research doctoral award and was nominated by the McGill biochemistry department for the Natural Sciences and Engineering Research Council of Canada doctoral prize for his thesis entitled “Nramp metal transporters: Insights into their structure, function and subcellular targeting”.

Steven Lam practices in the biotechnology and pharmaceutical areas, and has particular expertise in the areas of biochemistry, cell and molecular biology, immunology, vaccinology, genetics, genomics and proteomics.

Steven Lam
Ph.D., Technical Adviser - Patents
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  • Areas of practice
  • Professional Affiliations
    Intellectual Property Institute of Canada (IPIC)
  • Publications
    Czachorowski, M., Lam-Yuk-Tseung, S., Cellier, M., Gros, P., "Transmembrane topology of the mammalian Slc11a2 iron transporter", Biochemistry, 2009 (in press)
    Lam-Yuk-Tseung, S., Picard, V., Gros, P., "Identification of a tyrosine-based motif (YGSI) in the amino terminus of Nramp1 (SLC11A1) important for lysosomal targeting", Journal of Biological Chemistry, 281(42):31677-88, 2006
    Lam-Yuk-Tseung, S., Camaschella, C., Iolascon, A., Gros, P., "A novel R416C mutation in human DMT1 (SLC11A2) displays pleiotropic effects on function and causes microcytic anemia and hepatic iron overload", Blood Cells, Molecules and Diseases, 36:347-354, 2006
    Lam-Yuk-Tseung, S., Gros, P., "Distinct Targeting and Recycling Properties of Two Isoforms of the Iron Transporter DMT1 (NRAMP2, Slc11A2)", Biochemistry, 45:2294-2301, 2006
    "Nramp Metal Transporters: Insights into their structure, function, and subcellular targeting", Doctoral Thesis, 2006
    Forbes, J., Lam-Yuk-Tseung, S., Gros, P., Chapter 8.8.10 Modulation of Iron Availability at the Host-Pathogen Interface in Phagocytic Cells, "EcoSal-Escherichia coli and Salmonella: cellular and molecular biology", Editors: A. Böck et al., ASM Press, Washington D.C., June 2006
    Lam-Yuk-Tseung, S., Touret, N., Grinstein, S., Gros, P., "Carboxyl-Terminus Determinants of the Iron Transporter DMT1/SLC11A2 Isoform II (-IRE/1B) Mediate Internalization from the Plasma Membrane into Recycling Endosomes", Biochemistry, 44:12149-12159, 2005
    Lam-Yuk-Tseung, S., Mathieu, M., Gros, P., "Functional characterization of the E399D DMT1/NRAMP2/SLC11A2 protein produced by an exon 12 mutation in a patient with microcytic anemia and iron overload", Blood Cells, Molecules, and Diseases, 35:212-216, 2005
    Fortier, A., Min-Oo, G., Forbes, J., Lam-Yuk-Tseung, S., Gros, P., "Single gene effects in mouse models of host : pathogen interactions", Journal of Leukocyte Biology, 77:868-877, Review, 2005
    Touret, N., Martin-Orozco, N., Paroutis, P., Furuya, W., Lam-Yuk-Tseung, S., Forbes, J., Gros, P., Grinstein, S., "Molecular and cellular mechanisms underlying iron transport deficIency in microcytic anemia", Blood, 104:1526-1533, 2004
    Jabado, N., Lam-Yuk-Tseung, S., Forbes. J., Gros, P., "Natural resistance-associated macrophage protein 1 in mice", The Nramp Family, Editor: Mathieu Cellier and Philippe Gros, Eurekah.com and Klumer Academic / Plenum Publishing, 2004
    Lam-Yuk-Tseung, S., Gros, P., "Genetic control of susceptibility to bacterial infections in mouse models", Cellular Microbiology, 5:299-313, Review, 2003
    Lam-Yuk-Tseung, S., Govoni, G., Forbes, J., Gros, P., "Iron transport by Nramp2/DMT1:pH regulation of transport by 2 histidines in transmembrane domain 6", Blood, 101:3699-3707, 2003
  • Experiences
    2007-2008 Senior Scientist, Pfizer Vaccine Research (previously Coley Pharmaceutial Group), Ottawa
    2004 Lab Instructor, Department of biochemistry, McGill University
    1998 Research Assistant, McGill Cancer Center, McGill University
    1997 Research Assistant, Douglas Hospital Research Center
  • Continuing Education
    2008 “Vaccines: Development and Evaluation of Efficacy”, Foundation for Advanced Education in the Sciences, National Institutes of Health, Bethesda, Maryland
    2006 “Introduction to the Pharmaceutical Industry in Canada”, McGill University
    2004 “Behavior in Organizations”, McGill University
  • Education
    2006 Ph.D., Biochemistry, McGill University
    1999 B.Sc. (Honors), Biochemistry, McGill University
  • Scholarships
    2007 Nominated by McGill Biochemistry Department for NSERC Doctoral Prize
    2004-2005 McGill Faculty of Medicine Award
    2001-2004 Canadian Institutes of Health Research Doctoral Award
    1991-2001 FRSQ-FCAR-Santé Masters Award
    1996-1999 E. & M. Wilson Undergraduate Entrance Scholarship, McGill University

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